#4 The Radiologically isolated syndrome

BrainWaves: A Neurology Podcast

• Episode: #4 The Radiologically isolated syndrome
• Website: BrainWaves: A Neurology Podcast
• Feed URL: http://feeds.soundcloud.com/users/soundcloud:users:214831941/sounds.rss
• Duration: 00:19:21
• Published: 2016-05-01 04:44

Dr. Clyde Markowitz relays his account of the Radiologically Isolated Syndrome and his approach to managing it. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision making in routine clinical practice. The content in this episode was vetted and approved by Clyde Markowitz for broadcast. REFERENCES 1. Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL and Pelletier D. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology. 2009;72:800-5. 2. Barkhof F, Filippi M, Miller DH, Scheltens P, Campi A, Polman CH, Comi G, Ader HJ, Losseff N and Valk J. Comparison of MRI criteria at first presentation to predict conversion to clinically definite multiple sclerosis. Brain. 1997;120 ( Pt 11):2059-69. 3. Granberg T, Martola J, Kristoffersen-Wiberg M, Aspelin P and Fredrikson S. Radiologically isolated syndrome--incidental magnetic resonance imaging findings suggestive of multiple sclerosis, a systematic review. Multiple sclerosis. 2013;19:271-80. 4. Okuda DT, Mowry EM, Cree BA, Crabtree EC, Goodin DS, Waubant E and Pelletier D. Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome. Neurology. 2011;76:686-92. 5. Lebrun C, Bensa C, Debouverie M, Wiertlevski S, Brassat D, de Seze J, Rumbach L, Pelletier J, Labauge P, Brochet B, Tourbah A, Clavelou P and Club Francophone de la Sclerose en P. Association between clinical conversion to multiple sclerosis in radiologically isolated syndrome and magnetic resonance imaging, cerebrospinal fluid, and visual evoked potential: follow-up of 70 patients. Archives of neurology. 2009;66:841-6. 6. Giorgio A, Stromillo ML, Rossi F, Battaglini M, Hakiki B, Portaccio E, Federico A, Amato MP and De Stefano N. Cortical lesions in radiologically isolated syndrome. Neurology. 2011;77:1896-9. 7. Amato MP, Hakiki B, Goretti B, Rossi F, Stromillo ML, Giorgio A, Roscio M, Ghezzi A, Guidi L, Bartolozzi ML, Portaccio E, De Stefano N and Italian RISMSSG. Association of MRI metrics and cognitive impairment in radiologically isolated syndromes. Neurology. 2012;78:309-14. 8. Goodin DS and Bates D. Treatment of early multiple sclerosis: the value of treatment initiation after a first clinical episode. Multiple sclerosis. 2009;15:1175-82.